SHOW / EPISODE

Ayahuasca Is Not for Everyone with Dr. Jeff McNairy l Indigenous Ritutals, Sacred Rules, and Healing Trauma Safely at Rythmia

Season 15 | Episode 360
1h 17m | Sep 8, 2026

What if the key to healing trauma, addiction, depression, and other deeply rooted emotional patterns lies beyond the tools of conventional medicine? In this fascinating episode, we sit down with Dr. Jeff McNairy, Chief Medical Officer at Rythmia and a pioneer at the intersection of Western psychology and indigenous plant medicine, to explore the transformative potential of ayahuasca. Dr. Jeff explains how this powerful medicine may influence the brain, including synaptic plasticity, while emphasizing the critical importance of safety, screening, intention, and the “set and setting” surrounding the experience. He also shares insights into trauma, women’s emotional health, supporting highly sensitive people, and why some individuals may be drawn to plant medicine after conventional approaches haven’t delivered lasting results. Whether you’re curious about ayahuasca or simply interested in the future of mental and emotional healing, this conversation offers a thought-provoking look at what may be possible when we expand the definition of medicine.

Dr. Jeff McNairy, Psy.D., M.P.H. is a pioneer in the mental health revolution and Chief Medical Officer at Rythmia, the world’s first and only medically licensed ayahuasca retreat. With over 18,000 success stories and a 98% transformation rate, Dr. Jeff is leading the healing work at Rythmia, guiding people from all walks of life - including doctors, veterans, therapists, and those who have tried everything else toward emotional breakthroughs, recovery from trauma, and lasting transformation.

Supported by influential figures such as Kelly Slater, MLK III, Jack Canfield and comedian Ron White, who serve on the board, along with Hollywood A-listers like Terrence Howard, Rythmia helps individuals reconnect with their true selves in a way that traditional medicine often overlooks. For over 25 years, Dr. Jeff has worked at the intersection of Western psychology and indigenous medicine, helping thousands break free from PTSD, addiction, and depression. As a former Clinical Director of Passages Malibu, the world’s most successful luxury rehab center, he’s seen firsthand where traditional treatments fail - leading him to explore the power of alternative therapies.

SHOW NOTES:

0:48 Welcome to the podcast!

2:47 ABout Dr. Jeff McNairy

3:50 Welcome him to the show!

4:40 Why Ayahuasca?

5:55 About Iboga

7:13 How Ayahuasca works

9:24 Who it’s not for

12:25 Pre-trip cardiac work-up 

14:28 Safety at Rythmia

15:16 Schizophrenia

17:19 Indigenous cultural practices

19:15 When Westerners take Aya

19:59 About Shamanism

22:49 Importance of Set & Setting

25:26 Abuse & trauma in plant medicine

28:27 Women’s emotional & mental health

30:49 First discovery of Ayahuasca

33:31 Mechanisms of Action

36:50 Synaptic plasticity

37:55 Purging on Ayahuasca

44:39 How to prepare for visiting Rythmia

47:20 The main reasons people do Aya

51:30 Rythmia facilities & schedule

57:08 Supporting Empaths

1:07:25 Dosing Aya

1:11:40 Where to learn more

1:15:24 Ayahuasca in a nutshell

1:16:40 Thanks for tuning in!

RESOURCES:

Website: Rythmia

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Renee Belz & Lauren Sambataro
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