The Science of Regenerating Teeth and Restoring Smiles with Dr. Paul Sharpe

Season 1 | Episode 1
1h 6m | Jul 14, 2022

When we talk about living healthier for longer we must also include oral health, which plays a crucially important role in physical and mental health. According to the World Health Organization, over a billion people worldwide (~20% of the human population) experience trauma to their teeth at some point in their life, which can lead to tooth loss and lower quality of life.

Current treatments are costly, lengthy, and often require additional procedures throughout the patient's life, which can be financially and emotionally draining.

Scientists working on the dental regeneration technology (known as "Biotooth") aim to create a treatment that could regenerate your damaged or lost tooth using your stem cells.

We talk all about Biotooth with none other than Dr. Paul Sharpe, who is one of the pioneers and leaders in this field.

Dr. Paul Sharpe is head of the Department of Craniofacial Development and Stem Cell Biology at the historic King's College London, which is a wellspring of biomedical pioneers and innovation. As department head, Dr. Sharpe leads multiple academic research groups consisting of world-class biomedical researchers aiming to unravel the causes of diseases and translate discoveries into treatments to improve health worldwide.

Dr. Sharpe's research focuses on the molecular control of tooth development, dental stem cell biology, and stem-cell-based therapies in clinical dentistry. He's been at this for 30 plus years and counting, publishing over 300 research papers to date.

In 2004 Dr. Sharpe was awarded the Craniofacial Biology Research Award by the International Association for Dental Research, in recognition of his contribution to the understanding of how teeth develop. There's no one else better to talk with about this amazing Biotooth technology, which has the potential to restore smiles and improve an incredible amount of lives.

In this interview with Dr. Sharpe, we focus on how Biotooth came to be, its current status, where it's headed in the near future, and what needs to happen for it to become a clinical treatment.

For all questions related to Biotooth and Dr. Sharpe's work, please send all questions and comments to our team here:

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