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In this episode we saunter through a vitamin D guideline that provides a super summary resource, we look at why genetic testing for caffeine may be available for 'normal' athletes sooner than you think, and realise again how gender biased Sports nutrition research is.

This is the last show in this series. I do hope to have another series soon. Thank you to anyone listening. I hope you have enjoyed this as much as I have.

Zhou Y, Guo X, Liu Z, Sun D, Liang Y, Shen H, Li X, Mu J, Liu J, Cao G, Chen M. 6-week time-restricted eating improves body composition, maintains exercise performance, without exacerbating eating disorder in female DanceSport dancers. J Int Soc Sports Nutr. 2024 Dec;21(1):2369613. doi: 10.1080/15502783.2024.2369613. Epub 2024 Jun 21. PMID: 38904148; PMCID: PMC11195454.

Loftfield E, O'Connell CP, Abnet CC, Graubard BI, Liao LM, Beane Freeman LE, Hofmann JN, Freedman ND, Sinha R. Multivitamin Use and Mortality Risk in 3 Prospective US Cohorts. JAMA Netw Open. 2024 Jun 3;7(6):e2418729. doi: 10.1001/jamanetworkopen.2024.18729. PMID: 38922615; PMCID: PMC11208972.

Ineichen BV, Furrer E, Grüninger SL, Zürrer WE, Macleod MR. Analysis of animal-to-human translation shows that only 5% of animal-tested therapeutic interventions obtain regulatory approval for human applications. PLoS Biol. 2024 Jun 13;22(6):e3002667. doi: 10.1371/journal.pbio.3002667. PMID: 38870090; PMCID: PMC11175415.

Demay MB, Pittas AG, Bikle DD, Diab DL, Kiely ME, Lazaretti-Castro M, Lips P, Mitchell DM, Murad MH, Powers S, Rao SD, Scragg R, Tayek JA, Valent AM, Walsh JME, McCartney CR. Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2024 Jul 12;109(8):1907-1947. doi: 10.1210/clinem/dgae290. PMID: 38828931.

Aragon AA, Schoenfeld BJ, Wildman R, Kleiner S, VanDusseldorp T, Taylor L, Earnest CP, Arciero PJ, Wilborn C, Kalman DS, Stout JR, Willoughby DS, Campbell B, Arent SM, Bannock L, Smith-Ryan AE, Antonio J. International society of sports nutrition position stand: diets and body composition. J Int Soc Sports Nutr. 2017 Jun 14;14:16. doi: 10.1186/s12970-017-0174-y. PMID: 28630601; PMCID: PMC5470183.

Barreto G, Esteves GP, Marticorena F, Oliveira TN, Grgic J, Saunders B. Caffeine, CYP1A2 Genotype, and Exercise Performance: A Systematic Review and Meta-ana

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

In this episode we look at the results in Nature Medicine of the Zoe study and think about what might have made it a stronger paper and what questions are still not answered. We talk about an antibiotic cream that may prevent viral infections and finally a Nutri-sante cohort study that shows the potential dangers of emulsifiers, which are a very common ingredient in many of our common sports supplements.

Podcast 39

Mao T, Kim J, Peña-Hernández MA, Valle G, Moriyama M, Luyten S, Ott IM, Gomez-Calvo ML, Gehlhausen JR, Baker E, Israelow B, Slade M, Sharma L, Liu W, Ryu C, Korde A, Lee CJ, Silva Monteiro V, Lucas C, Dong H, Yang Y; Yale SARS-CoV-2 Genomic Surveillance Initiative; Gopinath S, Wilen CB, Palm N, Dela Cruz CS, Iwasaki A. Intranasal neomycin evokes broad-spectrum antiviral immunity in the upper respiratory tract. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2319566121. doi: 10.1073/pnas.2319566121. Epub 2024 Apr 22. PMID: 38648490; PMCID: PMC11067057.

Salame C, Javaux G, Sellem L, Viennois E, de Edelenyi FS, Agaësse C, De Sa A, Huybrechts I, Pierre F, Coumoul X, Julia C, Kesse-Guyot E, Allès B, Fezeu LK, Hercberg S, Deschasaux-Tanguy M, Cosson E, Tatulashvili S, Chassaing B, Srour B, Touvier M. Food additive emulsifiers and the risk of type 2 diabetes: analysis of data from the NutriNet-Santé prospective cohort study. Lancet Diabetes Endocrinol. 2024 May;12(5):339-349. doi: 10.1016/S2213-8587(24)00086-X. PMID: 38663950.

Bermingham KM, Linenberg I, Polidori L, Asnicar F, Arrè A, Wolf J, Badri F, Bernard H, Capdevila J, Bulsiewicz WJ, Gardner CD, Ordovas JM, Davies R, Hadjigeorgiou G, Hall WL, Delahanty LM, Valdes AM, Segata N, Spector TD, Berry SE. Effects of a personalized nutrition program on cardiometabolic health: a randomized controlled trial. Nat Med. 2024 May 8. doi: 10.1038/s41591-024-02951-6. Epub ahead of print. PMID: 38714898.

https://usrtk.org/industry-pr/science-media-centre/

https://www.sciencemediacentre.org/expert-reaction-to-study-looking-at-emulsifiers-and-type-2-diabetes/

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

What difference will 500m make to the ideal physiology for a rower. When should you go for cold immersion and when hot. Is training harder if you are on the hormonal contraceptive pill. Could that be a good thing. We skip through these and other questions trying to see if anything is clear or as muddy as a cold tub after a rugby team had been through it.

Ref:

Nash E, Nicoll A, Batt N, George J, Perananthan V, Prince D, Wallace M, Gow P, Vaz K, Chitturi S, Flores JE, Braund A, Bonnichsen M, Riordan S, Humphris J, Duong T, McKenzie C, Liu K, Strasser SI. Drug-induced liver injury from selective androgen receptor modulators, anabolic-androgenic steroids and bodybuilding supplements in Australia. Aliment Pharmacol Ther. 2024 Apr;59(8):953-961. doi: 10.1111/apt.17906. Epub 2024 Feb 19. PMID: 38372012.

Thorpe RT. Post-exercise Recovery: Cooling and Heating, a Periodized Approach. Front Sports Act Living. 2021 Sep 1;3:707503. doi: 10.3389/fspor.2021.707503. PMID: 34541521; PMCID: PMC8440788.

Astridge DJ, Peeling P, Goods PSR, Girard O, Watts SP, Dennis MC, Binnie MJ. Shifting the Energy Toward Los Angeles: Comparing the Energetic Contribution and Pacing Approach Between 2000- and 1500-m Maximal Ergometer Rowing. Int J Sports Physiol Perform. 2023 Nov 28;19(2):133-141. doi: 10.1123/ijspp.2023-0216. PMID: 38016454.

Sautillet B, Bourdillon N, Millet GP, Lemaître F, Cozette M, Delanaud S, Ahmaïdi S, Costalat G. Hot water immersion: Maintaining core body temperature above 38.5°C mitigates muscle fatigue. Scand J Med Sci Sports. 2024 Jan;34(1):e14503. doi: 10.1111/sms.14503. Epub 2023 Sep 25. PMID: 37747708.

Bischof K, Stafilidis S, Bundschuh L, Oesser S, Baca A, König D. Influence of specific collagen peptides and 12-week concurrent training on recovery-related biomechanical characteristics following exercise-induced muscle damage-A randomized controlled trial. Front Nutr. 2023 Nov 16;10:1266056. doi: 10.3389/fnut.2023.1266056. PMID: 38035363; PMCID: PMC10687431.

Oxfeldt M, Pedersen AB, Hørmann D, Lind JH, Larsen EB, Aagaard P, Hansen M. Influence of Second-Generation Oral Contraceptives on Muscle Recovery after Repeated Resistance Exercise in Trained Females. Med Sci Sports Exerc. 2024 Mar 1;56(3):499-510. doi: 10.1249/MSS.0000000000003316. Epub 2023 Oct 11. PMID: 38356164.

Windfeld-Mathiasen J, Heerfordt IM, Dalho

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

In this episode we review a mix of sleep and menstrual cycle articles. We look at the impact of sleep on viral infections, the right length of naps and the impact of sharing rooms. Then studies looking at injuries in different stages of the cycle and confirmation that it is still not something that is discussed as openly as needed. 

Podcast 37

Radke J, Meinhardt J, Aschman T, Chua RL, Farztdinov V, Lukassen S, Ten FW, Friebel E, Ishaque N, Franz J, Huhle VH, Mothes R, Peters K, Thomas C, Schneeberger S, Schumann E, Kawelke L, Jünger J, Horst V, Streit S, von Manitius R, Körtvélyessy P, Vielhaber S, Reinhold D, Hauser AE, Osterloh A, Enghard P, Ihlow J, Elezkurtaj S, Horst D, Kurth F, Müller MA, Gassen NC, Melchert J, Jechow K, Timmermann B, Fernandez-Zapata C, Böttcher C, Stenzel W, Krüger E, Landthaler M, Wyler E, Corman V, Stadelmann C, Ralser M, Eils R, Heppner FL, Mülleder M, Conrad C, Radbruch H. Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19. Nat Neurosci. 2024 Feb 16. doi: 10.1038/s41593-024-01573-y. Epub ahead of print. PMID: 38366144.

Costa JA, Figueiredo P, Lastella M, Nakamura FY, Guilherme J, Brito J. Comparing Sleep in Shared and Individual Rooms During Training Camps in Elite Youth Soccer Players: A Short Report. J Athl Train. 2023 Jan 1;58(1):79-83. doi: 10.4085/1062-6050-0042.22. PMID: 35380678; PMCID: PMC9913052.

Mesas AE, Núñez de Arenas-Arroyo S, Martinez-Vizcaino V, Garrido-Miguel M, Fernández-Rodríguez R, Bizzozero-Peroni B, Torres-Costoso AI. Is daytime napping an effective strategy to improve sport-related cognitive and physical performance and reduce fatigue? A systematic review and meta-analysis of randomised controlled trials. Br J Sports Med. 2023 Apr;57(7):417-426. doi: 10.1136/bjsports-2022-106355. Epub 2023 Jan 23. PMID: 36690376.

Walsh NP, Kashi DS, Edwards JP, Richmond C, Oliver SJ, Roberts R, Izard RM, Jackson S, Greeves JP. Good perceived sleep quality protects against the raised risk of respiratory infection during sleep restriction in young adults. Sleep. 2023 Jan 11;46(1):zsac222. doi: 10.1093/sleep/zsac222. PMID: 36112383; PMCID: PMC9832516.

Wynne-Ellis MM, Mursu JJ, Tuomainen TP, Bertone-Johnson E, Salonen JT, Virtanen JK. Dietary fat quality and serum androgen concentrations in middle-aged men. Eur J Clin Nu

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

In this episode we review an article by a group of dieticians saying that youtube videos by non-dieticans are of poor quality, look into the world of the Alkaline diet, and get an update on an exciting biomarker for the Med Diet.

Podcast 36

Kiss A, Soós S, Temesi Á, Unger-Plasek B, Lakner Z, Tompa O. Evaluation of the reliability and educational quality of YouTube™ videos on sport nutrition topics. J Int Soc Sports Nutr. 2023 Dec;20(1):2278632. doi: 10.1080/15502783.2023.2278632. Epub 2023 Nov 12. PMID: 37953602; PMCID: PMC10653641.

Knapik JJ, Trone DW, Steelman RA, Farina EK, Lieberman HR. Prevalence and adverse effects of sport-related nutritional supplements (sport drinks, bars, and gels) in the military before and during the COVID-19 pandemic: the US Military Dietary Supplement Use Study. J Int Soc Sports Nutr. 2023 Dec;20(1):2277246. doi: 10.1080/15502783.2023.2277246. Epub 2023 Nov 10. PMID: 37947831; PMCID: PMC10653656.

Yalcinkaya N, Isik O, Beyleroglu M, Erdogdu D, Cicek G, Novak D. Effects of 8-week alkaline diet and aerobic exercise on body composition, aerobic performance, and lipid profiles in sedentary women. Front Nutr. 2024 Jan 4;10:1339874. doi: 10.3389/fnut.2023.1339874. PMID: 38239837; PMCID: PMC10794351.

Sobiecki JG, Imamura F, Davis CR, Sharp SJ, Koulman A, Hodgson JM, Guevara M, Schulze MB, Zheng JS, Agnoli C, Bonet C, Colorado-Yohar SM, Fagherazzi G, Franks PW, Gundersen TE, Jannasch F, Kaaks R, Katzke V, Molina-Montes E, Nilsson PM, Palli D, Panico S, Papier K, Rolandsson O, Sacerdote C, Tjønneland A, Tong TYN, van der Schouw YT, Danesh J, Butterworth AS, Riboli E, Murphy KJ, Wareham NJ, Forouhi NG. A nutritional biomarker score of the Mediterranean diet and incident type 2 diabetes: Integrated analysis of data from the MedLey randomised controlled trial and the EPIC-InterAct case-cohort study. PLoS Med. 2023 Apr 27;20(4):e1004221. doi: 10.1371/journal.pmed.1004221. PMID: 37104291; PMCID: PMC10138823.

https://www.weightwatchers.com/us/blog/weight-loss/alkaline-diet

https://www.mrc-epid.cam.ac.uk/blog/2023/04/27/biomarkers-health-benefits-mediterranean-diet/

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

In this episode we run through at a small but interesting study of the impact of the menstrual cycle on the fuels the body uses. We question if we should be going to Industry funded research for our articles on benefits of carbohydrates and we then finish with a article on probiotics improving protein absorption and muscle gain in elite vegan athletes. 

Lee SJL, Sim MP, VAN Rens FECA, Peiffer JJ. Fatigue Resistance Is Altered during the High-Hormone Phase of Eumenorrheic Females but Not Oral Contraceptive Users. Med Sci Sports Exerc. 2024 Jan 1;56(1):92-102. doi: 10.1249/MSS.0000000000003289. Epub 2023 Aug 29. PMID: 37699150.

Gibson LP, Giordano GR, Bidwell LC, Hutchison KE, Bryan AD. Acute Effects of Ad Libitum Use of Commercially Available Cannabis Products on the Subjective Experience of Aerobic Exercise: A Crossover Study. Sports Med. 2023 Dec 26. doi: 10.1007/s40279-023-01980-4. Epub ahead of print. PMID: 38147185.

Rollo I, Williams C. Carbohydrate Nutrition and Skill Performance in Soccer. Sports Med. 2023 Dec;53(Suppl 1):7-14. doi: 10.1007/s40279-023-01876-3. Epub 2023 Jul 8. PMID: 37421586; PMCID: PMC10721660.

Fritz P, Fritz R, Bóday P, Bóday Á, Bató E, Kesserű P, Oláh C. Gut microbiome composition: link between sports performance and protein absorption? J Int Soc Sports Nutr. 2024 Dec;21(1):2297992. doi: 10.1080/15502783.2023.2297992. Epub 2023 Dec 27. PMID: 38151716; PMCID: PMC10763846.

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

We run through a selection of interesting articles, all of which demonstrate key flaws that we keep seeing in nutrition research. Testing at the wrong time, wrong timeframe to followup for that testing, competing interests that blow the mind. Articles that demonstrate the researchers deeply held beliefs rather than take the science and understanding forward. Enjoy!

Podcast 34

Clauss M, Skattebo Ø, Rasen Dæhli M, Ditta Valsdottir T, Ezzatkhah Bastani N, Ivar Johansen E, Jensen Kolnes K, Steen Skålhegg B, Jensen J. Carbohydrate Ingestion during Prolonged Cycling Improves Next-Day Time Trial Performance and Alters Amino Acid Concentrations. Med Sci Sports Exerc. 2023 Dec 1;55(12):2228-2240. doi: 10.1249/MSS.0000000000003264. Epub 2023 Aug 2. PMID: 37535337.

Jardine WT, Aisbett B, Kelly MK, Burke LM, Ross ML, Condo D, Périard JD, Carr AJ. The Effect of Pre-Exercise Hyperhydration on Exercise Performance, Physiological Outcomes and Gastrointestinal Symptoms: A Systematic Review. Sports Med. 2023 Nov;53(11):2111-2134. doi: 10.1007/s40279-023-01885-2. Epub 2023 Jul 25. PMID: 37490269; PMCID: PMC10587316.

Fensham NC, Govus AD, Peeling P, Burke LM, McKay AKA. Factors Influencing the Hepcidin Response to Exercise: An Individual Participant Data Meta-analysis. Sports Med. 2023 Oct;53(10):1931-1949. doi: 10.1007/s40279-023-01874-5. Epub 2023 Jun 22. PMID: 37347443.

Naveed S, Sallinen T, Eloranta AM, Skog H, Jalkanen H, Brage S, Ekelund U, Pentikäinen H, Savonen K, Lakka TA, Haapala EA. Effects of 2-year dietary and physical activity intervention on cognition in children-a nonrandomized controlled trial. Scand J Med Sci Sports. 2023 Nov;33(11):2340-2350. doi: 10.1111/sms.14464. Epub 2023 Aug 9. PMID: 37555467.

Khan TA, Lee JJ, Ayoub-Charette S, Noronha JC, McGlynn N, Chiavaroli L, Sievenpiper JL. WHO guideline on the use of non-sugar sweeteners: a need for reconsideration. Eur J Clin Nutr. 2023 Nov;77(11):1009-1013. doi: 10.1038/s41430-023-01314-7. Epub 2023 Sep 18. PMID: 37723261; PMCID: PMC10630128.

Tay W, Quek R, Lim J, Kaur B, Ponnalagu S, Henry CJ. Plant-based alternative proteins-are they nutritionally more advantageous? Eur J Clin Nutr. 2023 Nov;77(11):1051-1060. doi: 10.1038/s41430-023-01328-1. Epub 2023 Aug 14. PMID: 37580584.

Chapman S, Roberts J, Roberts AJ, Ogden H, Izard R, Smith L, Chichger H, Stuszczak L and Rawcliffe AJ (2023) Pre-sleep protein supplementation does not impro

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

In this episode I review some practical changes to the way we can prescribe/recommend our athletes take iron supplements. I then sit on the sidelines and enjoy the fighting between factions on the sides of the Ultra Processed Food safety/blame war and am very glad not to be in the line of fire and feel some empathy for those involved. We finish with some articles on weight loss with different carbohydrates, the impact of fibre on cancer risk and an older article on post menopausal muscle strength.

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

This episode we review a couple of articles that challenge the common perceptions for coffee and fasting, and decide if they will change our practice. We look at the useful points from the new IOC REDS consensus and enjoy an interesting Fish Oil Supplement article. 

Podcast 32

Svart M, Nielsen MM, Rittig N, Hansen M, Møller N, Gravholt CH. Oral 3-hydroxybuturate ingestion acutely lowers circulating testosterone concentrations in healthy young males. Scand J Med Sci Sports. 2023 Oct;33(10):1976-1983. doi: 10.1111/sms.14441. Epub 2023 Jun 28. PMID: 37377131.

https://www.aspetar.com/Journal/viewarticle.aspx?id=586

White L, Losciale JM, Squier K, Guy S, Scott A, Prior JC, Whittaker JL. Combined hormonal contraceptive use is not protective against musculoskeletal conditions or injuries: a systematic review with data from 5 million females. Br J Sports Med. 2023 Sep;57(18):1195-1202. doi: 10.1136/bjsports-2022-106519. Epub 2023 May 24. PMID: 37225254.

Mountjoy M, Ackerman KE, Bailey DM, Burke LM, Constantini N, Hackney AC, Heikura IA, Melin A, Pensgaard AM, Stellingwerff T, Sundgot-Borgen JK, Torstveit MK, Jacobsen AU, Verhagen E, Budgett R, Engebretsen L, Erdener U. 2023 International Olympic Committee's (IOC) consensus statement on Relative Energy Deficiency in Sport (REDs). Br J Sports Med. 2023 Sep;57(17):1073-1097. doi: 10.1136/bjsports-2023-106994. PMID: 37752011.

Heileson JL, Machek SB, Harris DR, Tomek S, de Souza LC, Kieffer AJ, Barringer ND, Gallucci A, Forsse JS, Funderburk LK. The effect of fish oil supplementation on resistance training-induced adaptations. J Int Soc Sports Nutr. 2023 Dec;20(1):2174704. doi: 10.1080/15502783.2023.2174704. PMID: 36822153; PMCID: PMC9970203.

Zhang Z, Wang M, Yuan S, Larsson SC, Liu X. Genetically predicted coffee and tea consumption and risk of intracranial aneurysm. Eur J Clin Nutr. 2023 Aug;77(8):811-814. doi: 10.1038/s41430-023-01295-7. Epub 2023 Jun 13. PMID: 37311867.

Sakamaki T, Hara M, Kayaba K, Kotani K, Ishikawa S. Coffee Consumption and Incidence of Subarachnoid Hemorrhage: The Jichi Medical School Cohort Study. J Epidemiol. 2016;26(2):71-5. doi: 10.2188/jea.JE20150092. Epub 2015 Oct 10. PMID: 26460383; PMCID: PMC4728117.

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

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We start with a look at a article providing further evidence BMI is unhelpful, moving onto the effect of low carb diets on bowel inflammation and then a time restricted eating study. The main player this week is the WHO sweetener review...spoiler they don't think they are good for you long term and are pushing back against the wave of industry funded positive spin on the observational studies hinting at increased long term mortality. Finally a great study on what is actually in your herbal supplement. 

Podcast 31

Cohen PA, Avula B, Katragunta K, Travis JC, Khan I. Presence and Quantity of Botanical Ingredients With Purported Performance-Enhancing Properties in Sports Supplements. JAMA Netw Open. 2023 Jul 3;6(7):e2323879. doi: 10.1001/jamanetworkopen.2023.23879. PMID: 37459101; PMCID: PMC10352857.

Lin S, Cienfuegos S, Ezpeleta M, Gabel K, Pavlou V, Mulas A, Chakos K, McStay M, Wu J, Tussing-Humphreys L, Alexandria SJ, Sanchez J, Unterman T, Varady KA. Time-Restricted Eating Without Calorie Counting for Weight Loss in a Racially Diverse Population : A Randomized Controlled Trial. Ann Intern Med. 2023 Jul;176(7):885-895. doi: 10.7326/M23-0052. Epub 2023 Jun 27. PMID: 37364268.

https://www.health.harvard.edu/staying-healthy/the-dangers-of-the-herb-ephedra

https://www.who.int/publications/i/item/9789240073616

https://www.sweeteners.org/isa-response-to-who-guideline-on-low-no-calorie-sweeteners/

McKay AKA, Wallett AM, McKune AJ, Périard JD, Saunders P, Whitfield J, Tee N, Heikura IA, Ross MLR, Sharma AP, Costa RJS, Burke LM. The Impact of a Short-Term Ketogenic Low-Carbohydrate High-Fat Diet on Biomarkers of Intestinal Epithelial Integrity and Gastrointestinal Symptoms. Int J Sport Nutr Exerc Metab. 2023 Aug 11:1-11. doi: 10.1123/ijsnem.2023-0009. Epub ahead of print. PMID: 37567573.

Visaria A, Setoguchi S. Body mass index and all-cause mortality in a 21st century U.S. population: A National Health Interview Survey analysis. PLoS One. 2023 Jul 5;18(7):e0287218. doi: 10.1371/journal.pone.0287218. PMID: 37405977; PMCID: PMC10321632.

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

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This week we look at a recent BMJ paper on sweeteners vs sugar for health of diabetic patients and compare to some of the past papers we have studied in this area. We enjoy an excellent short intervention study on the impact of pre-meal almonds and wait for the larger studies to follow. Finally a look at the impact of Heat on your sleep low- train low adaptations. 

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

A slightly noisey podcast due to nearby building work.

My favourite this month was a superb Australian article proving how poor labeling is in supplements - the industry must do better than this. A review through some interesting options for pre race optimisation such as coffee mouth rinsing, defecation, topical bicarbonate, some interesting new ideas to explore.

References

Held S, Rappelt L, Donath L. Acute and Chronic Performance Enhancement in Rowing: A Network Meta-analytical Approach on the Effects of Nutrition and Training. Sports Med. 2023 Jun;53(6):1137-1159. doi: 10.1007/s40279-023-01827-y. Epub 2023 Apr 25. PMID: 37097415; PMCID: PMC10185652.

Martinez IG, Mika AS, Biesiekierski JR, Costa RJS. The Effect of Gut-Training and Feeding-Challenge on Markers of Gastrointestinal Status in Response to Endurance Exercise: A Systematic Literature Review. Sports Med. 2023 Jun;53(6):1175-1200. doi: 10.1007/s40279-023-01841-0. Epub 2023 Apr 15. PMID: 37061651; PMCID: PMC10185635.

Gurton WH, Greally J, Chudzikiewicz K, Gough LA, Lynn A, Ranchordas MK. Beneficial effects of oral and topical sodium bicarbonate during a battery of team sport-specific exercise tests in recreationally trained male athletes. J Int Soc Sports Nutr. 2023 Dec;20(1):2216678. doi: 10.1080/15502783.2023.2216678. PMID: 37227399; PMCID: PMC10215010.

Wei CC, Condello G, Yang AL, Yu SH, Liao YH, Chen CY, Hsu CC, Huang CY, Kuo CH. Defecation enhances cerebral perfusion and delays fatigue in elite triathletes. J Int Soc Sports Nutr. 2023 Dec;20(1):2206380. doi: 10.1080/15502783.2023.2206380. PMID: 37102434; PMCID: PMC10142319.

Taheri Karami G, Hemmatinafar M, Koushkie Jahromi M, Nemati J, Niknam A. Repeated mouth rinsing of coffee improves the specific-endurance performance and jump performance of young male futsal players. J Int Soc Sports Nutr. 2023 Dec;20(1):2214108. doi: 10.1080/15502783.2023.2214108. PMID: 37190757; PMCID: PMC10190181.

Mannino A, Daly A, Dunlop E, Probst Y, Ponsonby AL, van der Mei IAF; Ausimmune Investigator Group; Black LJ. Higher consumption of ultra-processed foods and increased likelihood of central nervous system demyelination in a case-control study of Australian adults. Eur J Clin Nutr. 2023 May;77(5):611-614. doi: 10.1038/s41430-023-01271-1. Epub 2023 Feb 8. PMID: 36754977; PMCID: PMC10169648.

Tian Y, Ra

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

In this episode we enjoy a article that clarifies why your performance should not dip on a high fat low carb diet although we are still waiting for the proof and why the answer to your fatigue and unusual symptoms may still be 'covid' even a year post infection. In a more cheerful papers, a year of hard training is still helping with diabetic control 10 years later.

References:
Podcast 28

Chen Y, Chen Z, Pan L, Ma ZM, Zhang H, Li XJ, Li X. Effect of Moderate and Vigorous Aerobic Exercise on Incident Diabetes in Adults With Obesity: A 10-Year Follow-up of a Randomized Clinical Trial. JAMA Intern Med. 2023 Mar 1;183(3):272-275. doi: 10.1001/jamainternmed.2022.6291. PMID: 36716009; PMCID: PMC9887527.

Noakes TD, Prins PJ, Volek JS, D'Agostino DP, Koutnik AP. Low carbohydrate high fat ketogenic diets on the exercise crossover point and glucose homeostasis. Front Physiol. 2023 Mar 28;14:1150265. doi: 10.3389/fphys.2023.1150265. PMID: 37057184; PMCID: PMC10086139.

Puschhof J, Elinav E. Human microbiome research: Growing pains and future promises. PLoS Biol. 2023 Mar 17;21(3):e3002053. doi: 10.1371/journal.pbio.3002053. PMID: 36930679; PMCID: PMC10057739.

Melin AK, Areta JL, Heikura IA, Stellingwerff T, Torstveit MK, Hackney AC. Direct and indirect impact of low energy availability on sports performance. Scand J Med Sci Sports. 2023 Mar 9. doi: 10.1111/sms.14327. Epub ahead of print. PMID: 36894187.

Dennis A, Cuthbertson DJ, Wootton D, Crooks M, Gabbay M, Eichert N, Mouchti S, Pansini M, Roca-Fernandez A, Thomaides-Brears H, Kelly M, Robson M, Hishmeh L, Attree E, Heightman M, Banerjee R, Banerjee A. Multi-organ impairment and long COVID: a 1-year prospective, longitudinal cohort study. J R Soc Med. 2023 Mar;116(3):97-112. doi: 10.1177/01410768231154703. Epub 2023 Feb 14. PMID: 36787802; PMCID: PMC10041626.

Vanheest JL, Rodgers CD, Mahoney CE, De Souza MJ. Ovarian suppression impairs sport performance in junior elite female swimmers. Med Sci Sports Exerc. 2014 Jan;46(1):156-66. doi: 10.1249/MSS.0b013e3182a32b72. PMID: 23846160.

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

In this episode we look at an excellent review that attempts to help us understand nitrates. We get frustrated by studies jumping into the 'fasting vs exercise' debate and the 'plant vs fish' debate with very selective use of their data.

References:

Podcast 27

Gibbons TD, Cotter JD, Ainslie PN, Abraham WC, Mockett BG, Campbell HA, Jones EMW, Jenkins EJ, Thomas KN. Fasting for 20 h does not affect exercise-induced increases in circulating BDNF in humans. J Physiol. 2023 Jan 11. doi: 10.1113/JP283582. Epub ahead of print. PMID: 36631068.

Ong KL, Marklund M, Huang L, Rye KA, Hui N, Pan XF, Rebholz CM, Kim H, Steffen LM, van Westing AC, Geleijnse JM, Hoogeveen EK, Chen YY, Chien KL, Fretts AM, Lemaitre RN, Imamura F, Forouhi NG, Wareham NJ, Birukov A, Jäger S, Kuxhaus O, Schulze MB, de Mello VD, Tuomilehto J, Uusitupa M, Lindström J, Tintle N, Harris WS, Yamasaki K, Hirakawa Y, Ninomiya T, Tanaka T, Ferrucci L, Bandinelli S, Virtanen JK, Voutilainen A, Jayasena T, Thalamuthu A, Poljak A, Bustamante S, Sachdev PS, Senn MK 2nd, Rich SS, Tsai MY, Wood AC, Laakso M, Lankinen M, Yang X, Sun L, Li H, Lin X, Nowak C, Ärnlöv J, Risérus U, Lind L, Le Goff M, Samieri C, Helmer C, Qian F, Micha R, Tin A, Köttgen A, de Boer IH, Siscovick DS, Mozaffarian D, Wu JH. Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts. BMJ. 2023 Jan 18;380:e072909. doi: 10.1136/bmj-2022-072909. PMID: 36653033; PMCID: PMC9846698.

Srour B, Chazelas E, Druesne-Pecollo N, Esseddik Y, de Edelenyi FS, Agaësse C, De Sa A, Lutchia R, Debras C, Sellem L, Huybrechts I, Julia C, Kesse-Guyot E, Allès B, Galan P, Hercberg S, Pierre F, Deschasaux-Tanguy M, Touvier M. Dietary exposure to nitrites and nitrates in association with type 2 diabetes risk: Results from the NutriNet-Santé population-based cohort study. PLoS Med. 2023 Jan 17;20(1):e1004149. doi: 10.1371/journal.pmed.1004149. PMID: 36649248; PMCID: PMC9844911.

Aengevaeren VL, Mosterd A, Bakker EA, Braber TL, Nathoe HM, Sharma S, Thompson PD, Velthuis BK, Eijsvogels TMH. Exercise Volume Versus Intensity and the Progression of Coronary Atherosclerosis in Middle-Aged and Older Athletes: Findings From the MARC-2 Study. Circulation. 2023 Jan 4. doi: 10.1161/CIRCULATIONAHA.122.061173. Epub ahead of print. PMID: 36597865.

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

Firsty a smattering of proof that flavonoids are great for managing ageing changes, but still no good evidence they help our athletes perform any better. Then a nice microbiome paper that tells us why some mice seem to be lazier than others. Can we stretch this to human athletes? Also we ask where can we shoehorn in continuous glucose monitors - it looks fancy and must be useful for our patients....
Apologies for forgetting the name of a leading UK Medical Nutrition Academic - of course it was Prof T Spector.

References:

Parr EB, Kouw IWK, Wheeler MJ, Radford BE, Hall RC, Senden JM, Goessens JPB, van Loon LJC, Hawley JA. Eight-hour time-restricted eating does not lower daily myofibrillar protein synthesis rates: A randomized control trial. Obesity (Silver Spring). 2023 Feb;31 Suppl 1:116-126. doi: 10.1002/oby.23637. Epub 2022 Dec 22. PMID: 36546330.

Bowler AM, Whitfield J, Marshall L, Coffey VG, Burke LM, Cox GR. The Use of Continuous Glucose Monitors in Sport: Possible Applications and Considerations. Int J Sport Nutr Exerc Metab. 2022 Dec 26:1-12. doi: 10.1123/ijsnem.2022-0139. Epub ahead of print. PMID: 36572039.

Rendón MY, Dos Santos Scholz MB, Bragagnolo N. Physical characteristics of the paper filter and low cafestol content filter coffee brews. Food Res Int. 2018 Jun;108:280-285. doi: 10.1016/j.foodres.2018.03.041. Epub 2018 Mar 15. PMID: 29735059.

Safe S, Jayaraman A, Chapkin RS, Howard M, Mohankumar K, Shrestha R. Flavonoids: structure-function and mechanisms of action and opportunities for drug development. Toxicol Res. 2021 Jan 20;37(2):147-162. doi: 10.1007/s43188-020-00080-z. PMID: 33868973; PMCID: PMC8007671.

Ruiz-Iglesias P, Gorgori-González A, Massot-Cladera M, Castell M, Pérez-Cano FJ. Does Flavonoid Consumption Improve Exercise Performance? Is It Related to Changes in the Immune System and Inflammatory Biomarkers? A Systematic Review of Clinical Studies since 2005. Nutrients. 2021 Mar 30;13(4):1132. doi: 10.3390/nu13041132. PMID: 33808153; PMCID: PMC8065858.

Parmenter BH, Bondonno CP, Murray K, Schousboe JT, Croft K, Prince RL, Hodgson JM, Bondonno NP, Lewis JR. Higher Habitual Dietary Flavonoid Intake Associates With Less Extensive Abdominal Aortic Calcification in a Cohort of Older Women. Arterioscler Thromb Vasc Biol. 2022 Dec;42(12):1482-1494. doi: 10.1161/ATVBAHA.122.318408. Epub 2022 Nov 3. PMID: 36325901.

Holland TM, Agarwal P, Wang Y, Dhana K, Leur

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

In short - no. But we review a series of recent articles trying to pick away at the inner workings of these markers. We try and avoid the pitfalls of black and white answers and steer around the icebergs of simplification. In addition, beetroot and blood pressure, water use and ibuprofen on the intestine.

References:

Lundy B, McKay AKA, Fensham NC, Tee N, Anderson B, Morabito A, Ross MLR, Sim M, Ackerman KE, Burke LM. The Impact of Acute Calcium Intake on Bone Turnover Markers during a Training Day in Elite Male Rowers. Med Sci Sports Exerc. 2023 Jan 1;55(1):55-65. doi: 10.1249/MSS.0000000000003022. Epub 2022 Aug 12. PMID: 35977107; PMCID: PMC9770130.

McKenna ZJ, Ducharme JB, Berkemeier QN, Specht JW, Fennel ZJ, Gillum TL, Deyhle MR, Amorim FT, Mermier CM. Ibuprofen Increases Markers of Intestinal Barrier Injury But Suppresses Inflammation at Rest and After Exercise in Hypoxia. Med Sci Sports Exerc. 2023 Jan 1;55(1):141-150. doi: 10.1249/MSS.0000000000003032. Epub 2022 Sep 5. PMID: 36069803.

Astridge DJ, Peeling P, Goods PSR, Girard O, Hewlett J, Rice AJ, Binnie MJ. Rowing in Los Angeles: Performance Considerations for the Change to 1500 m at the 2028 Olympic Games. Int J Sports Physiol Perform. 2022 Nov 29;18(1):104-107. doi: 10.1123/ijspp.2022-0231. PMID: 36448487.

Burtscher J, Vanderriele PE, Legrand M, Predel HG, Niebauer J, O'Keefe JH, Millet GP, Burtscher M. Could Repeated Cardio-Renal Injury Trigger Late Cardiovascular Sequelae in Extreme Endurance Athletes? Sports Med. 2022 Dec;52(12):2821-2836. doi: 10.1007/s40279-022-01734-8. Epub 2022 Jul 18. PMID: 35851948; PMCID: PMC9691495.

Nash D, Hughes MG, Butcher L, Aicheler R, Smith P, Cullen T, Webb R. IL-6 signaling in acute exercise and chronic training: Potential consequences for health and athletic performance. Scand J Med Sci Sports. 2023 Jan;33(1):4-19. doi: 10.1111/sms.14241. Epub 2022 Oct 8. PMID: 36168944.

Rogerson D, Aguilar Mora FA, Young JS, Klonizakis M. No effect of nitrate-rich beetroot juice on microvascular function and blood pressure in younger and older individuals: a randomised, placebo-controlled double-blind pilot study. Eur J Clin Nutr. 2022 Oct;76(10):1380-1386. doi: 10.1038/s41430-022-01115-4. Epub 2022 Mar 29. PMID: 35352014; PMCID: PMC9550618.

Toro-Román V, Siquier-Coll J, Bartolomé I, Grijota FJ, Muñoz D, Maynar-Mariño M. Influence of physical training on intracellular and extracellular zinc conce

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

This week we will dip a toe into Lipidomics,  the direction of cholesterol tests in the future; not just looking at lipid blood levels but using the lipid tests as a reflection of changes within our cell membranes. We then look at a state of play article for current available lipid blood tests and how to interpret panels, a keto diet study and a remind ourselves how good bariatric surgery is for people. 

References:

Episode 24

Lauber C, Gerl MJ, Klose C, Ottosson F, Melander O, Simons K. Lipidomic risk scores are independent of polygenic risk scores and can predict incidence of diabetes and cardiovascular disease in a large population cohort. PLoS Biol. 2022 Mar 3;20(3):e3001561. .

Yin X, Willinger CM, Keefe J, Liu J, Fernández-Ortiz A, Ibáñez B, Peñalvo J, Adourian A, Chen G, Corella D, Pamplona R, Portero-Otin M, Jove M, Courchesne P, van Duijn CM, Fuster V, Ordovás JM, Demirkan A, Larson MG, Levy D. Lipidomic profiling identifies signatures of metabolic risk. EBioMedicine. 2020 Jan;51:102520. doi: 10.1016/j.ebiom.2019.10.046. Epub 2019 Dec 24. 

Wolrab D, Jirásko R, Cífková E, Höring M, Mei D, Chocholoušková M, Peterka O, Idkowiak J, Hrnčiarová T, Kuchař L, Ahrends R, Brumarová R, Friedecký D, Vivo-Truyols G, Škrha P, Škrha J, Kučera R, Melichar B, Liebisch G, Burkhardt R, Wenk MR, Cazenave-Gassiot A, Karásek P, Novotný I, Greplová K, Hrstka R, Holčapek M. Lipidomic profiling of human serum enables detection of pancreatic cancer. Nat Commun. 2022 Jan 10;13(1):124.

German CA, Shapiro MD. Assessing Atherosclerotic Cardiovascular Disease Risk with Advanced Lipid Testing: State of the Science. Eur Cardiol. 2020 Jul 15;15:e56. 

Mentias A, Aminian A, Youssef D, Pandey A, Menon V, Cho L, Nissen SE, Desai MY. Long-Term Cardiovascular Outcomes After Bariatric Surgery in the Medicare Population. J Am Coll Cardiol. 2022 Apr 19;79(15):1429-1437. 

Brenton JN, Lehner-Gulotta D, Woolbright E, Banwell B, Bergqvist AGC, Chen S, Coleman R, Conaway M, Goldman MD. Phase II study of ketogenic diets in relapsing multiple sclerosis: safety, tolerability and potential clinical benefits. J Neurol Neurosurg Psychiatry. 2022 Jun;93(6):637-644. doi: 10.1136/jnnp-2022-329074. Epub 2022 Apr 13. 

Antonio L, Wu FCW, Moors H, Matheï C, Huhtaniemi IT, Rastrelli G, Dejaeger M, O'Neill TW, Pye SR, Forti G, Maggi M, Casanueva FF, Slowikowska-Hilczer J, Punab M, Tournoy J, Vanderschueren D; E

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

In this podcast we cover the evolving evidence that low carbohydrate diets are not going to kill you in the ways that we keep getting told. We also look at the 1 year impact of even mild covid and look at what form your carbohydrate needs to be in mid race (spoiler - it does not really matter as long as you can tolerate it).

Below are the references for this episode in no particular order...

Moholdt T, Parr EB, Devlin BL, Debik J, Giskeødegård G, Hawley JA. The effect of morning vs evening exercise training on glycaemic control and serum metabolites in overweight/obese men: a randomised trial. Diabetologia. 2021 Sep;64(9):2061-2076. doi: 10.1007/s00125-021-05477-5. Epub 2021 May 19. PMID: 34009435; PMCID: PMC8382617.

Haganes KL, Silva CP, Eyjólfsdóttir SK, Steen S, Grindberg M, Lydersen S, Hawley JA, Moholdt T. Time-restricted eating and exercise training improve HbA1c and body composition in women with overweight/obesity: A randomized controlled trial. Cell Metab. 2022 Oct 4;34(10):1457-1471.e4. doi: 10.1016/j.cmet.2022.09.003. PMID: 36198292.

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Whitaker M, Elliott J, Chadeau-Hyam M, Riley S, Darzi A, Co

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

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In this review of the current nutrition literature we look at some articles highlighting the dangers of our processed food dependency, look at a rare bird in nutrition - a well designed RCT, and discuss a LEA case report.

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Send us a text

We balance the tea/coffee debate with a large tea cohort paper review. Then a exploration through recent articles on the reduced VO2 post covid, the importance of our mitochondria in health and neurodegenerative disease and why sweeteners are evil. 

This podcast is a lighthearted review of the medical literature and Dr Matheson has enormous respect for all scientific researchers and could not do a job as hard as theirs.
The information presented is the personal opinion of the healthcare professional and is not a substitute for seeking professional advice. It is based on interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it’s release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen.

Dr Matheson is not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast. Reliance on information provided in this podcast is solely at the listeners risk.

The podcast is designed to be used generate learning discussions and for education only. It is not recommended to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.