SHOW / EPISODE

#222 AFib Stroke Prevention: WATCHMAN, DOACs, and the CHAMPION-AF Trial | Beyond Journal Club Segment with NEJM Group

31m | Oct 28, 2026

If your patient asks you about a left atrial appendage closure device, what should you tell them?Ā Ā 

Ā In the latest episode of the Beyond Journal Club podcast from CORE IM and NEJM Group, the hosts will help you:Ā 

  • Understand the trade-offs: stroke prevention, bleeding, procedural risks, and medications afterward.Ā 
  • Build clinical judgment: weigh which approach may better serve the individual patient, beyond the trial’s headline.Ā 
  • Learn from thoughtful counseling: hear how you might discuss the evidence, acknowledge uncertainty, and explore what matters to your patients.


šŸ”¹Sponsor: ACP MKSAP Oakstone CME

Use the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP7​


šŸ”¹Transcript and Show Notes Ā 

01:09 | What the Watchman is, and why it should work?

05:58 | The checkered history: PROTECT-AF and PREVAIL

09:06 | The plot continues: PRAGUE-17, OPTION, OCEAN, and CLOSURE-AF

12:35 | CHAMPION-AF: the biggest test yet

15:03 | Reading the fine print

19:23 | A local solution to a systemic problem

22:45 | How patients hear about it

25:44 | So what do we tell our patients?

29:52 | Takeaways


Tags: IMCore, Internal Medicine, Medical Education, WATCHMAN device, Atrial Fibrillation, Cardiology, DOAC Anticoagulation, Primary Care, Hospital Medicine



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